In the LSD-bound crystal composition, the aspect chain of the lid residue L209EL2 forms intensive hydrophobic contacts with both of those LSD and surrounding residues in TMs III, IV, and V (Figure 4C). If the lid moved apart to show the binding pocket in simulation, numerous of these contacts broke. https://lsdaztec9999752.blogthisbiz.com/42023109/considerations-to-know-about-lsd-vial