Bixin and norbixin are natural food colourants synthesised from Bixa orellana L seeds. This study explores the mechanism of apocarotenoids (bixin and norbixin) on the aggressive B16 murine melanoma as an anti-cancer agent. The apocarotenoids inhibited the cell viability of B16 melanoma in a time- and concentration-dependent manner. https://www.ealisboa.com/best-buy-Freya-Viva-La-Fiesta-Plunge-Bikini-Top-Multi-great-buy/