Here, we present that conolidine, a all-natural analgesic alkaloid used in conventional Chinese drugs, targets ACKR3, thereby providing supplemental proof of a correlation among ACKR3 and soreness modulation and opening option therapeutic avenues for the treatment method of Long-term soreness. Along with the described previously mentioned monomeric alkaloids, There's https://giordanoo581zyx3.wikigiogio.com/user